Question: After 4 people presented to a hospital with an unknown disease, an investigation to monitor these patients as well as the development of a new cases began on January 1, 2013 and ended on December 31, 2013. Among 1,000 people included in the monitoring program, a total of 10 cases of the disease were identified during the year of 2013 (4 initial, plus 6 new cases).For those cases, the diagram below depicts the time of case recognition, periods of observation during the study, and vital status at the time of the termination of observation. An arrow at the start of the diagram (patients 1-4) indicates that the start of disease occurred before the investigation began. Assume all individuals were alive at the beginning of study and there were no losses to follow-up or deaths not otherwise specified. Thus, assume the remaining 990 people were alive and disease-free as of January 1, 2014.

1. Calculate the prevalence of disease on January 1, 2013; July 1, 2013; and December 31, 2013.
2. Calculate the cumulative incidence of disease in 2013.
3. Calculate the cumulative incidence of death in 2013.

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