A 65 year old woman with a low bone density in 1992 was treated with alendronate through the year 19


Question: A 65 year old woman with a low bone density in 1992 was treated with alendronate through the year 1999. Bone density was measured irregularly over this period. The results for change in bone density of the lumbar spine are shown in table 1.

Change in bone density, lumbar spine, over time

Visit \[\left( i \right)\] Time from baseline (months) \[\left( {{t}_{i}} \right)\] Bone density, lumbar spine (gm/\[c{{m}^{2}}\]) \[\left( {{x}_{i}} \right)\]
1 0 0.797
2 8 0.806
3 18 0.817
4 48 0.825
5 64 0.837
6 66 0.841
7 79 0.886
8 92 0.881

Note: \[\sum\limits_{i=1}^{8}{{{t}_{i}}}\] =375, \[\sum\limits_{i=1}^{8}{{{x}_{i}}=6.69}\] , \[\sum\limits_{i=1}^{8}{t_{i}^{2}}\] =25,849, \[\sum\limits_{i=1}^{8}{x_{i}^{2}}\] =5.60197, \[\sum\limits_{i=1}^{8}{{{x}_{i}}{{t}_{i}}}\] =320.874

Provide a measure of association between bone density of the lumbar spine and bone density of the femoral neck.

Price: $2.99
Solution: The solution consists of 1 page
Solution Format: Word Document

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