Alcohol Use During Pregnancy and Spontaneous Abortion In their paper “Cigarette, Alcohol, and Coffee

Question: Alcohol Use During Pregnancy and Spontaneous Abortion

In their paper “Cigarette, Alcohol, and Coffee Consumption and Spontaneous Abortion”, American Journal of Public Health (1992), Armstrong et al. reported the following results regarding alcohol use (drinks/week) and spontaneous abortion. These results are contained in the file Alcohol and Spontaneous Abortions.JMP.

Alcohol Use (Drinks per Week)	Number of Pregnancies	Spontaneous Abortions	Spontaneous Abortion (%)
a None	33164	6793
b 1 – 2	9099	2068
c 3 – 6	3069	776
d 7 – 20	1527	456
e 21+	287	98

a) For each level of alcohol use estimate the probability that a woman who becomes pregnant will undergo a spontaneous abortion. Stated another way, estimate the percentage of women in each alcohol use category that will have a spontaneous abortion. Place the results in the provided column. Discuss. (3 pts.)

b) Conduct a test to determine if there is a relationship between alcohol use during pregnancy and spontaneous abortions. Summarize your findings. (4 pts.)

c) For each category of alcohol use find the odds ratio associated with each use level relative to women who do not drink during pregnancy. Hint: You might find it useful to construct a 2 X 2 table for each drinking level relative to nondrinkers. Discuss. (6 pts.)

You can do this in JMP by excluding and hiding all drink levels except for the nondrinkers and the level of alcohol use of interest.

Highlight the rows to temporarily remove. Select both Exclude/Unexclude and High/Unhide from the Rows pull-down menu. Fit Y by X now will allow us to compare 1-2 drinks/week to nondrinkers in terms of risk of spontaneous abortion. To restore all cases select Clear Row States from the same menu, then move on to the next group