A clinical trial is conducted to determine the effectiveness of drug A in preventing premature labor
Question: A clinical trial is conducted to determine the effectiveness of drug A in preventing premature labor. Thirty women are randomly divided into a treatment group and a placebo group. Birth weights of infants born to the women are given below. Investigators wish to compare the birth weights of infants born to mothers within the treatment group with the infants born to mothers within the placebo group.
RQ: Is there a difference in the average birth weight in infants between those mothers who received drug A and those mothers who received the placebo?
Ho: mean birth weight treatment group = mean birth weight placebo group
Ha: mean birth weight treatment group does not equal mean birth weight placebo group
Step 1: Create the Variables
a. Start SPSS.
b. Click the Variable View tab.
c. Enter the variables therapy and weight in the rows.
d. Create value labels for therapy with 1 = drug A and 2 = placebo
The Data:
| Participant | Therapy | Weight | Participant | Therapy | Weight |
| 1 | 1 | 6.9 | 16 | 2 | 6.4 |
| 2 | 1 | 7.6 | 17 | 2 | 6.7 |
| 3 | 1 | 7.3 | 18 | 2 | 5.4 |
| 4 | 1 | 7.6 | 19 | 2 | 8.2 |
| 5 | 1 | 6.8 | 20 | 2 | 5.3 |
| 6 | 1 | 7.2 | 21 | 2 | 6.6 |
| 7 | 1 | 8.0 | 22 | 2 | 5.8 |
| 8 | 1 | 5.5 | 23 | 2 | 5.7 |
| 9 | 1 | 5.8 | 24 | 2 | 6.2 |
| 10 | 1 | 7.3 | 25 | 2 | 7.1 |
| 11 | 1 | 8.2 | 26 | 2 | 7.0 |
| 12 | 1 | 6.9 | 27 | 2 | 6.9 |
| 13 | 1 | 6.8 | 28 | 2 | 5.6 |
| 14 | 1 | 5.7 | 29 | 2 | 4.2 |
| 15 | 1 | 8.6 | 30 | 2 | 6.8 |
Step 2: Enter the data
a. Click Data View tab.
b. Enter the data for the 30 participants.
Step 3: Analyze the Data
a. From the menu bar, select Analyze>Compare Means> Independent-Samples T Test.
b. Select weight and move it into Test Variables box.
c. Select therapy and move in into Grouping Variable box, click Define Groups and enter a 1 beside drug A and a 2 beside placebo.
d. Click Continue.
e. Click OK.
Step 4: Interpret the Results
Effect Size =
Cohen (1988) specified values of d of .2, .5, and .8 as corresponding to small, medium, and large effect sizes.
Expression of Results in APA Format:
Deliverables: Word Document
