[Steps Shown] A study of 13 children with asthma compared single inhaled doses of formoterol (F) and salbutamol (S). The outcome measured was the child’s


Question: A study of 13 children with asthma compared single inhaled doses of formoterol (F) and salbutamol (S). The outcome measured was the child’s peak expiratory flow (PEF)

eight hours after treatment.

Child F S Child F S Child F S Child F S

1 310 270 4 310 260 7 410 390 10 250 210

2 385 370 5 410 380 8 320 290 11 380 350

3 400 310 6 370 300 9 330 365 12 340 260

13 220 90

Let mu denote the population mean of the difference between the PEF values for the F and S treatments. Perform a significance test for the null hyp. that mu = 0 against the two-sided alternative. Give a 95% confidence interval for mu.

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