[All Steps] Researchers hypothesize an association between the number of comorbid chronic diseases and cognitive function in individuals with Alzheimer’s
Question: Researchers hypothesize an association between the number of comorbid chronic diseases and cognitive function in individuals with Alzheimer’s Disease (AD). A study was conducted to evaluate this hypothesis. The number of comorbid chronic diseases was ascertained via self-report and categorized as: 0, 1-2, 3-4, or 5+. Global cognitive function was measured using the Mini-Mental State Exam (MMSE), which ranges from 0 to 30, with lower scores indicating worse cognitive functioning. The results of the study are presented in the Stata output below.
| Variable Name | Description | Codes/Values |
| chronic | Number of comorbid chronic diseases |
0 = 0 diseases, 1 = 1-2 diseases,
2 = 3-4 diseases, 3 = 5+ diseases |
| cognition | Score on the MMSE | Numeric, 0 to 30 |
- As can be seen in the provided codebook, the number of comorbid chronic diseases has been included in the model as a continuous variable ranging from 0 to 3 to represent the ordered categories (as opposed to including the exposure as a set of dummy variables). As a result, what assumption has been made about the relationship between the number of chronic diseases and scores on the MMSE?
- What is the average MMSE score for an individual with 4 comorbid chronic diseases?
- Calculate the 95% confidence interval for the slope and use this to draw a conclusion about the research hypothesis. Be sure to explain how you made this conclusion.
- Based only on the 95% confidence interval from c), what do you expect the p-value for the slope to be? Less than 0.05 or greater than 0.05?
Deliverable: Word Document 