[Solution] The following is an exerpt from Phytomedicine 2008 Jun;15(6-7):400-7. 2008 Jan 28. Boswellic acids: A leukotriene inhibitor also effective through
Question: The following is an exerpt from Phytomedicine 2008 Jun;15(6-7):400-7. 2008 Jan 28. Boswellic acids: A leukotriene inhibitor also effective through topical application in inflammatory disorders:
"Boswellic acids (BA), a natural mixture isolated from oleo gum resin of Boswellia serrata comprised of four major pentacyclic triterpene acids: beta-boswellic acid (the most abundant), 3-acteyl-beta-boswellic acid, 11-keto-beta-boswellic acid, and 3-acetyl-11-keto-beta-boswellic acid, is reported to be effective as anti-inflammatory, immunomodulatory, anti-tumor, anti-asthmatic and in Crohn's disease. It inhibits pro-inflammatory mediators in the body, specifically leukotrienes via inhibition of 5-lipoxygenase, the key enzyme of leukotriene synthesis, is the scientifically proved mechanism for its anti-inflammatory/anti-arthritic activity"
In an experiment, a researcher randomly assigns previously diagnosed asthmatic subjects into one of four groups: Placebo, 450mg dose, 900mg dose, 1350mg dose.
This study proceeds for approximately 6 months. At the end of six months, each subject donates a vial of blood and has their plasma levels of leukotrienB4 measured using chromatographic fractionation and radioimmunoassay. The results are shown below. All concentrations are in pg/ml:
| Placebo | 450 mg | 900mg | 1350 mg |
| 36 | 43 | 51 | 26 |
| 44 | 39 | 43 | 36 |
| 38 | 52 | 43 | 28 |
| 55 | 44 | 33 | 27 |
| 38 | 45 | 36 | 44 |
| 45 | 35 | 42 | 38 |
| 49 | 38 | 38 | 36 |
Using your roadmap, test the appropriate hypothesis and report your findings in APA format
Deliverable: Word Document 