Question: In a double blinded comparison of two ointments, containing calcipotriol or betamethasone, for the treatment of psoriasis, 345 subjects were given one ointment on the left side of the body and the other on the right side, being chosen at random. The severity of the condition was assessed by self-report as "cleared", "pronounced improvement", "slight improvement", "no change", or "worse" and by visual assessment as a score by the investigator.

The score was significantly lower \((P<0.001)\) for the calcipotriol side than the betamethasone side. Patients were more likely to report "cleared" or "pronounced improvement" on the calcipotriol side

1. Suggest three methods which could be used carry out the significance test on the scores. What assumptions would be required for each?
2. The self-assessment was recoded into two categories "cleared or pronounced improvement" or "little or no improvement". What methods could be used to carry out the significance test for the recoded data?
3. What can we conclude?

Price: $2.99

Solution: The downloadable solution consists of 2 pages
Deliverable: Word Document