Question: A researcher wants to know whether a drug decreases the frequency of seizures for severely epileptic patients. For a month before taking the drug each subject records their number of seizures. Each subjects then receives two months of drug therapy and for the second month the number of seizures is again recorded. The change in the number of seizures after one month of drug therapy is as follows for a group of n = 9 subjects:
[ -5 -1 -4 -3 -6 -8 0 +4 +1 ]

Is there an effect of the drug (use α = 0.01 and assume that all the necessary assumptions are satisfied)? Identify the type of experimental design used, the independent and dependent variables, and show all your work, including the values of all statistical quantities calculated.

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